Aller-Essentials contains a blend of nutrients and herbal extracts designed to maintain healthy seasonal immune function. EpiCor® Saccharomyces cerevisiae fermentate contains numerous immune-enhancing bioactive metabolites designed to support both innate and adaptive immune response. 
 
 
Research suggests that it enhances natural killer cell activation, B cell and T cell function, and salivary IgA levels. In a double-blind, placebo-controlled trial involving 96 subjects, EpiCor® supported nasal comfort during a 12-week period in the spring.
 
Additionally, it supported salivary IgA levels, an important first-line defense produced by the mucosal tissue. In a randomized, double-blind trial involving 75 individuals, Tinospora cordifolia provided significant support for a healthy immune response by maintaining normal nasal function as well as healthy neutrophil and eosinophil activity. 
 
 
A randomized, double-blind, placebo-controlled trial involving apple polyphenols reveals support for maintaining a healthy nasal lining and nasal function. 
 
 
Quercetin, hesperidin and vitamin C provide additional support for stabilizing mast cells.
 
 
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